Impairment of vestibulo-collic reflex and linear vestibulo-ocular reflex in pediatric-onset multiple sclerosis patients

This study aimed to examine the vestibulo-collic reflex (VCR) and linear vestibulo-ocular (lVOR) their correlation with brain lesions in pediatric-onset multiple sclerosis (POMS). The group consisted of 17 patients (34 ears) POMS (mean age 18.73 ± 2.02, mean at disease onset 14.64 1.36 years), control included 11 age-matched healthy subjects (22 ears). Ocular cervical Vestibular Evoked Myogenic Potentials (oVEMP cVEMP) were performed assess IVOR VCR pathways. Magnetic Resonance Imaging was evaluated group. In group, 47.05 % oVEMPs 17.64 cVEMPs abnormal, while all VEMPs normal oVEMP amplitude associated infratentorial lesion volume (r = −0.459, p 0.01) total brainstem cerebellum −0.450, 0.01). cVEMP asymmetry ratio correlated deep white matter 0.683, < 0.001). MVEMP scores found correlate only volumes 0.488, 0.04) region 0.573, VEMP abnormalities confirm that lVOR pathways may be affected early POMS. Routine use test, especially test is recommended as a useful tool follow-up patients.